Sneha, began her film career in 2001 film Malayalam film as a supporting artiste, however her major breakthrough came later that year in a Tamil language film, Ennavale opposite Madhavan. Later that year, she starred in the successful venture, Aanandham as well as a prestigious project for K. Balachandar in Parthale Paravasam, she finished the year with a foray into Telugu cinema, making two appearances in notable films.

In 2002, Sneha broke into the "big league". Unlike many other top actresses of her time, her acting was praised, and was likened to a modern day Revathi Menon. A total of 8 films, were released including her first major hit in Telugu with Hanuman Junction as well as other hits in Unnai Ninaithu and April Madhathil. Prestigious films with top actors also followed, such as King and Pammal K. Sambandam with Vikram and Kamal Haasan respectively.

After a successful previous year, Sneha became more aware with her choice of films, with only two releasing in 2003. The first being with a big actor, Vijay in Vaseegara, the second being a heroine-orientated double role in Parthiban Kanavu. The film became a commercial hit as well as winning plaudits for Sneha's portrayal of the double role.

2004 was a mixed year for the actress, with Jana, Bose, Venky and Adhu, a horror film, all failing at the box-office. However, Vasool Raja MBBS opposite Kamal Haasan became a commercial success, while her guest role in Autograph, another successful project, was praised.

Though she has acted in many Telugu films, the success of K Ragavendra Rao-directed mythological movie Sri Ramadasu (2006) helped Sneha to firm up her foothold in Telugu cinema. Her role in the movie, steeped in the bhakti culture, was well appreciated by moviegoers. Meanwhile, her Mollywood flick with Mammootty, Thuruppugulan (2006), was also a big hit. In Pudhupettai (2006), Sneha as a battered and bruised prostitute is a revelation. She is precise and poised in her portrayal.

Sneha has decided finally to revamp her homely image and go the glam way. Until now the audience have only been seeing Sneha in the homely roles. She has done some glamorous songs, but her current movie Pandi with Raghava Lawrence is way above any of those glamor roles that she has done before.

It is said that she has done very explicit scenes in this film Pandi which will act as a stepping stone in shedding her girl-next door image and will flood her with offers of the glamorous kind.

Director Raghavendra Rao who is well known for showing his heroines in the best possible and appealing ways in all his films is the director of this movie. Sneha is sure to bag a new set of young fans after this movie.